High Purity Pharmaceutical Intermediate CAS: 2418-14-6 Dimercaptosuccinic Acid

Quick detail:

Product Name: Dimercaptosuccinic acid

Synonym: 2, 3-dimercapto-butanedioicaci; 2, 3-dimercaptobutanedioicacid; 2, 3-dimercapto-succinicaci; Alpha, beta-dimercaptosuccinicacid; Suximer; 2, 3-DIMERCAPTOSUCCINIC ACID; DIMERCAPTOSUCCINIC ACID; Imercaptosuccinic Acid

CAS: 2418-14-6

MF: C4H6O4S2

MW: 182.22

Appearance: White crystalline powderDensity: 1.617 g/cm3

Flash point: 115.6 ° C

Boiling point: 267.6 ° C at 760 mmHg

Description:

The Dimercaptosuccinic acid, with its CAS registry number 2418-14-6, has the systematic name of 2, 3-disulfanylbutanedioic acid. For being a kind of white crystalline powder, it is soluble in caustic soda liquid. As to its usage, it is usually applied as the intermediate of sodium dimercaptosuccinate, and it could also be used as the detoxicant and health supplements.

Exposure Standards and Regulations

Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended; 21 U. S. C. 321-392).

The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed drug products, incl succimer, approved on the basis of safety and effectiveness by FDA under sections 505 and 507 of the Federal Food, Drug, and Cosmetic Act.

Application:

DMSA/Dimercaptosuccinic Acid is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMSA is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMSA can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.

 

Another application for DMSA is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMSA is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercury exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMSA challenge test "misleading" for the purposes of diagnosing mercury toxicity. Moreover, DMSA share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.

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1. Packing  :

A: Order under 20kg

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B: Order above 50kg

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2. Discreet packing would be introduced to you according to your quantity and where are you based .

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4. Tracking number would be provided as well . So you could get yourself prepared when parcel is arriving .

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We specialize in this field for many years, our  hormones exported to Overseas, to Europe, Africa, Asia and Americas and so on other country, and we have got very good feedback from our customers, and had Established long friendly relations of cooperation.

3. Great quality, purity and favourable.

Good quality is one of our secret success, welcome order the samples, MOQ just 10 grams.

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We have special way could ship 0.01 kilo to 3.5 kilo products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.

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