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12 KBNP Inc.

KITA DUNS

Country South Korea South Korea

Supplier Grade level3

Main products Himmvac Poultry Vaccines
Himmvac Swine Vaccines
Lifegard-T
AVANTE Injection

Product Information

Description

AVANTE injection contains the sodium salt of ceftiofur which is a broad spectrum antibiotic effective against gram-positive and gram-negative bacteria including β-lactamase producing microorganisms. Like other cephalosporins, ceftiofur is bactericidal by inhibition of cell wall synthesis.

In particular, AVANTE injection is often used for new born piglet colibacillosis, pleuropneumonia, pasteurella-pneumonia of weaning pig, calf pneumonia and shipping fever caused by pasteurella.

Characteristics

  • More effective
    AVANTE is a, bactericidal antibiotics, killing target pathogens. AVANTE is highly effective in treating respiratory diseases caused by the major pneumonia pathogens in pig and cattle.

  • More rapid
    When administered intramuscularly, plasma concentrations reachto 100 times higher than minimum inhibitory concentration(Mlc) for target respiratory pathogens within one hour.

  • More tolerable
    AVANTE is a safe product that doesn't irritate the injection site.

  • More convenient
    AVNATE is easily reconstituted without removing top of the cap and highly syringeable.

Bioavailability

Ceftiofur sodium is quickly absorbed within an hour after intramuscularly injection, reaches to a high initial peak and maintains for maximum 35 hours by therapeutic levers

Antibacterial activity of AVANTE injection

MICs for main pathogens isolated from pigs

Organism
No.tested
MIC
MIC90
Sensitivity (%)
A. pleuropneumonia
83
≤0.03~0.06
≤0.03
98.7%
P. multocida
74
≤0.03~0.06
≤0.03
99.2%
S. suis
94
≤0.03~1.0
0.25
99.6%
S. cholerasuis
50
1.0~2.0
1.0
97.8%
H. parasuis
76
0.0039~0.25
0.06
99.9%

MICs for main pathogens isolated from cattle

Organism
Antibiotics
MIC90
Sensitivity (%)
P. hemolitica
Ceftiofur
Spectinomycin
Tilmicosin
Ampicilin
Tetracycline
Sulfamethazine

<=0.03
64.0
8.0
82.0
32.0
512.0

100.0
83.5
69.1
60.5
57.0
46.2
P. multocida
Ceftiofur
Ampicilin
Tetracycline
Tilmicosin
<=0.03
8.0
16.0
8.0
100.0
88.1
71.1
58.0
H. somnus
Ceftiofur
Tetracycline
Tilmicosin
Ampicilin
<=0.03
1.0
4.0
1.0

100.0
98.2
90.4
90.1

Percentage of isolates sensitive to antibiotic

The results of this survey are that ceftiofur demonstrated the highest levels of sensitivity to commonly observed swine respiratorv infections

Case report of Swine application

Efficacy of ceftiofur in suckling piglet (14 days old)

 
Ceftiofur
Control
Difference
Mortality rate(%)
7.5
11.0
-31.8%
Average daily gain (Birth to weaning, g)
215
204
+5.4%

Under weight weaning pig (<3.6kg, %)

12.4
14.8
-16.2%

Efficacy for Actinobacillus pleuropneumonia(APP) in growin pig

 
Lung lesion(%)
No.of symptom(%)
Ceftiofur(25pigs)
3mg/kg
10.0
11 (44%)
Control(25pigs)
Saline
29.1
20 (80%)
Image
Company
KBNP Inc.

KBNP Inc.

Country South Korea South Korea

Supplier Grade level3

President
SONG, KI YEON
Address
254-18 Dugok-ri, Sinam-myeon, Yesan-gun, Chungcheongnam-do, 340-861 KOREA
Product Category
Medical Devices,Veterinary Instrument
No. of Total Employees
51-100
Company introduction

The most famous player in animal health industry in Korea, KBNP is a Korean manufacturer of animal health products including biologicals, injectables, water solubles, oral solutions, premixes, aquaculture and disinfectants for intensive livestock and poultry production and companion animals.
Founded in 1989, KBNP took over the animal vaccine business unit from Bayer Korea in December, 2001 and completed the latest model of biological production facilities complied to Korean Good Manufacturing Pracitce.

The company has grown into successful national player in biologicals and biosecurity. It produces highly immunogenic vaccine (Himmvac) and high quality innovative animal healty and hygiene products which are very famous and competitive in national market.
KBNP has highly profiled personnel resources both in marketing and sales department. It provides livestock farms throughout the country with fast and accurate analysis information. KBNP is doing its best to become a company that is trusted by the customers and provides reliable products.

In order to centralizing investment on the vaccine industry, which can be called the core of animal health business, the relocation of the vaccine facilities in Yesan acquired KVGMP.
For the costomers, company and shareholders to get along and grow together, KBNP put its company philosophy basis of basics and principles. KBNP will be also volunteered to be environment-friendly company.

Main Markets
  • Bangladesh Bangladesh ,
  • Hong Kong(China) Hong Kong(China) ,
  • Indonesia Indonesia ,
  • Malaysia Malaysia ,
  • Pakistan Pakistan