Apolipoprotein E (ApoE) Genotyping Kit

Apolipoprotein E (ApoE) Genotyping Kit

Negotiable Min Order Quantity Unit

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Place of Origin
South Korea
Payment Terms
Production method
Shipping / Lead Time
Negotiable / Negotiable
molecular diagnostic, realtime pcr, apolipoprotein e, alzheimer,
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Country / Year Established
South Korea South Korea / 2000
Business type
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Product name Apolipoprotein E (ApoE) Genotyping Kit Certification -
Category Other Chemicals
Chemical Reagents & Products
Ingredients -
Keyword molecular diagnostic , realtime pcr , apolipoprotein e , alzheimer Unit Size -
Brand name - Unit Weigh -
origin South Korea Stock -
Supply type - HS code -

Product Information


Apolipoprotein E (ApoE) Genotyping Kit


Real-Time PCR (or Multiplex allele-specific PCR) based assay system for the genotyping

of the ApoE gene SNP related to alzheimer’s disease

Genetic information

Apolipoprotein E (ApoE) consists of three isoforms: E2, E3 and E4. These three isoforms make six genotypes, (homozygous genotypes: E2/E2, E3/E3 E4/E4 and heterozygous genotypes: E2/E3, E2/E4, E3/E4). Isoform E2 is usually known as a protective isoform whereas isoform E4 is generally responsible for diseases. The predominant abnormalities are due to a single nucleotide polymorphism (SNP) of codon 112 (Cys/Arg) and codon 158 (Arg/Cys). The polymorphism has functional effects on the lipoprotein metabolism. ApoE is the primary ligand for two receptors, LDL receptors found in the liver and other tissues and ApoE specific receptors found in the liver. The co-ordinate interaction of these lipoprotein

complexes with their receptors forms the basis for the metabolic regulation of cholesterol. ApoE has been found to be associated with elevated cholesterol levels or lipid derangements that lead to various clinical problems like coronary heart diseases, strokes, periphery artery diseases, and diabetes mellitus. In addition to the genotype-phenotype associations with the cardiovascular disease, the alleles and isoforms of ApoE have been related to dementias, most commonly Alzheimer’s disease. Determining the genotype of ApoE is thus considered to be an important test for patients with the disease, as well as a precautionary test for healthy people.

Production Specification 



DiaPlexQ™ ApoE Genotyping Kit

DiaPlexC™ Apolipoprotein E (ApoE) Genotyping Kit

Detection target

ApoE genotype (Mutation T112C and T158C of ApoE gene)

E2/E2, E3/E3, E4/E4, E2/E3, E2/E4, E3/E4

Detection technology

Real-Time PCR

Conventional (End-point) Multiplex PCR

Specimen type







ABI 7500 / 7500 Fast Real-Time PCR System (Applied Biosystems) CFX96™ Real-Time PCR System (Bio-Rad)



ABI Veriti thermal Cycler (Applied

Biosystems) recommended


 PCR running time

 ~ 1 hr 30 min

 ~ 1 hr 30 min

* Please inquire us for compatible instrument information before use.  

Product Features

- HotStart PCR system : Ultra high specific and sensitive result

- UDG system : No carryover contamination (DiaPlexQ™)

- Multiplex PCR : Multiple targets in a single reaction

- Reliable system : Automatic Internal control (DiaPlexC™)

- Positive control included

- Easy-to-use master mix

- CE certification


1. Lepara O, Valjevac A, Alajbegovic A, Zaciragic A, Nakas-Icindic E (August 2009). Decreased serum lipids in patients with probable Alzheimer’s disease”. Bosn J Basic Med Sci 9 (3): 215-20.

2. Golomb BA, Evans MA (2008). “Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism”. Am J Cardiovasc Drugs 8 (6): 373-418

Result & Data interpretation



Ordering Information 


 Cat. No.



 Real-Time PCR



(20 reaction)

 DiaPlexQ™ ApoE Genotyping Kit


2X Multiplex Real-Time PCR Smart mix (ApoE)

Primer & Probe Mixture (ApoE 112)

Primer & Probe Mixture (ApoE 158)

T/T type Control DNA (ApoE 112)

T/C type Control DNA (ApoE 112)

C/C type Control DNA (ApoE 112)

T/T type Control DNA (ApoE 158)

T/C type Control DNA (ApoE 158)

C/C type Control DNA (ApoE 158)

Nuclease free Water



(100 reaction)



(End-point) PCR



(20 reaction)

 DiaPlexC™ Apolipoprotein E

(ApoE) Genotyping Kit



2X Multiplex PCR Smart mix (ApoE)

Primer Mixture (ApoE)

Standard Marker (ApoE)

Control Template (ApoE)

Nuclease free Water


SHG01-K100(100 reaction)




B2B Trade

Price (FOB) Negotiable transportation -
MOQ Negotiable Leadtime Negotiable
Payment Options Negotiable Shipping time Negotiable


Country / Year Established
South Korea South Korea / 2000
Business type



32, 3F Techno6ro Yuseong-gu Daejeon
Product Category
Other Chemicals
Year Established
No. of Total Employees
Company introduction
SolGent InC, established in 2000, is a technuical market leader in the field of molecular biology. Based on the research ecperiences in KAIST(Korea Advanced Institute of Science and Technology), we are launching the leading products which meet the unremitting needs of life science. Our major products are PCR related thermostable ploymerases, DNA ligase, RNA plymerases, Reverse Tranx-x-scriptase, and DNA ligase RNA polymerases, Reverse Transcriptase, of genetic analysis, we are also providing the sequencing and genotyping services. The products and services are so competitive in the quality as well as the price. Especially, we are proud of the recently developed novel products, SEQrooge and H-Taq. You can find them here and enjoy their performances. Thank you
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