Since taking NMN may help your body produce more NAD, it’s also important to consider the research behind the benefits of NAD. Studies investigating NAD shed light on its potential benefits: •It may increase longevity. In your cells, NAD activates a group of proteins called sirtuins, which help repair your DNA. The activity of sirtuins is linked to longevity. On the flip side, low-NAD levels are associated with age related diseases. •It may have protective effects on the brain. NAD is thought to modulate the production of a protein that helps guard cells against impairment of mitochondrial function and oxidative stress. These cellular stressors are related to some neurological diseases, including Alzheimer’s disease. •It may help reduce heart disease risk. Research in mice has found that high NAD levels in the blood reversed age-related arterial damage, which may help guard against heart disease. •It may protect against cancer. Elevated NAD levels may help protect cells against oxidative stress and DNA damage, which are associated with cancer development. •It may help with jet lag. Research suggests NAD may help adjust your internal clock, potentially helping ease jet lag or other circadian rhythm disorders. •It may help aging muscles. Research in older mice have shown that high blood NAD levels helped improve muscle function, strength, and endurance in older mice