CH2 Domain Library Construction

CH2 Domain Library Construction


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Place of Origin
U.S.A
Payment Terms
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Keyword
ch2 domain library construction
Category
Pharmaceuticals
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Creative Biolabs

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BIZ
Country / Year Established
U.S.A U.S.A / 2005
Business type
Manufacturer
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Product Information

Creative Biolabs offers the exclusive Hi-Affi™ phage display platform for custom CH2 domain antibody-like scaffold library construction. Through this proprietary technology, libraries with 100% precise mutant and over 1010 diversity can be generated. CH2 domain (CH2D), also known as nanoantibody (nAb), the immunoglobulin (Ig) constant CH2 domain, is critical for the Ig effector functions. The structure of the constant antibody domains is similar to that of the variable domains consisting of β-strands connected mostly with loops or short helices. CH2, is unique in that it exhibits very weak carbohydrate-mediated interchain protein-protein interactions.

 

 

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Creative Biolabs

Country / Year Established
U.S.A U.S.A / 2005
Membership
BIZ
Business type
Manufacturer

8

DUNS

President
Mr
Address
SUITE 203, 17 Ramsey Road, Shirley, NY 11967, USA
Product Category
Other Pharmaceutical Chemicals
Year Established
2005
Company introduction

 

Creative Biolabs is a leading company of recombinant antibody (rAb) discovery and manufacturing, providing high quality service to customers in academia and industry fields all over the world.
 
Our cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products and extensive service portfolio at the most competitive price. Our products range from antibody / peptide libraries, Biosimilar cell lines, Chimeric antigen receptor (CAR) products, antibody-drug conjugates (ADCs) to engineered antibodies such as therapeutic antibodies, nanobodies, bispecific antibodies and intrabodies. We also provide professional custom antibody discovery and engineering services, featuring phage display library construction, antibody humanization, chimerization, engineered antibody production (Fab, scFc, tribody, bispecific antibody, nanobody, minibody, etc.), antibody labeling, hybridoma/stable cell line development, membrane protein production and cGMP-manufacturing which enable larger scale antibody production for development of animal-based assays and clinical trials.

 

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